INFLUENCE OF GENETIC COPY NUMBER VARIANTS OF THE HUMAN GLUT3 GLUCOSE TRANSPORTER GENE SLC2A3 ON PROTEIN EXPRESSION, GLYCOLYSIS AND RHEUMATOID ARTHRITIS RISK: A GENETIC REPLICATION STUDY

Objectives: The gene encoding glucose transporter 3 (GLUT3, SLC2A3) is present in the human population at variable copy number.An overt disease phenotype of SLC2A3 copy number variants has not been reported; however, deletion of SLC2A3 has been previously reported to protect carriers from rheumatoid arthritis, implicating GLUT3 as a therapeutic tar

Abstract Background Morphogen signalling represents a key mechanism of developmental processes during animal development.Previously, several evolutionary conserved morphogen signalling pathways have been identified, and their players such as the morphogen receptors, morphogen modulating factors (MMFs) and the morphogens themselves have been studied

Generative AI (GenAI) can iPod Wire Harness generate high-resolution and complex content mimicking the creativity of humans, thereby benefiting industries such as gaming, entertainment, and product design.In recent times, AI-generated fake videos, commonly referred to as deepfakes, have become more commonplace and convincing.An additional deepfake

BackgroundVarious enhanced patient instructions (EPIs) have been used for bowel preparation (BP) and our previous meta-analysis also demonstrated the efficacy of EPIs in increasing the colonic polyp and adenoma detection rates; however, the optimal method for adequate BP has not yet been developed.ObjectiveWe performed a network meta-analysis to de

Brick cumbustion in Kaloran Village uses firewood and corncob as main fuel.Combustion using firewood and corncobs in burning bricks produce PM2.5 pollutants that can cause health problem including the eyes.Dry eye is a multifactorial disease of ocular surface in Flip Flop Sofa symptoms that include discomfort, visual disturbance and tear film insta